Thrombospondin-based antiangiogenic therapy
نویسندگان
چکیده
منابع مشابه
Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.
Recent studies indicate that continuous administration improves the antitumoral efficacy of angiogenesis inhibitors, as compared with intermittent dosing, suggesting a potential role of gene therapy in antiangiogenic tumor therapy. We established a tissue-engineered implant system for the continuous in vivo production of thrombospondin-2 (TSP-2), a potent endogenous inhibitor of tumor growth an...
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ژورنال
عنوان ژورنال: Microvascular Research
سال: 2007
ISSN: 0026-2862
DOI: 10.1016/j.mvr.2007.04.007